Guanidinium and Phosphonium Scaffolds Loaded with Silver Nanoparticles: Synthesis, Characterization, In Vitro Assessment of the Antibacterial Potential and Toxicity

New silver nanocomposites based on polysulfones of 2,2-diallyl-1,1,3,3-tetraethylguanidiniumchloride [poly(AGC–SO2)], tris(diethylamino)diallylaminophosphonium tetrafluoroborate [poly(DAAP–BF4–SO2)] and chloride [poly(DAAP–Cl–SO2)] have been developed. UV-spectroscopy, SEM XRD techniques were used to characterize the formation nanoparticles in copolymers. Antibacterial action new S. epidermidis 33 Escherichia coli (planktonic cells biofilms) was studied. The strongly inhibited biofilms coli. phosphonium a significant cytotoxic activity against RD MS line cells.